About Scottsdale Plastic Surgeon Dr. Lille
Dr. Lille was raised in Arizona and attended Brophy Prep. He graduated Summa Cum Laude with a BA from Cal-Berkeley and received his MD from the University of Arizona. Dr. Lille completed his Residency in General Surgery at the University of Washington, where he was also a Research Fellow in the Department of Vascular Surgery. He completed his Residency in Plastic Surgery, which also included a Plastic Burn Fellowship, at Southern Illinois University Medical Center. An Aesthetic Plastic Surgery Fellowship Specializing in Cosmetic Surgery took Dr. Lille to the Mayo Clinic Scottsdale where, following his aesthetic fellowship, he served as an associate in the Department of Plastic Surgery.


Dr. Lille, Board Certified by the American Board of Plastic Surgery, has authored more than 50 publications in his field. He has also lectured both nationally and around the world.
SEAN TOMAS LILLE, M.D., P.C.
10210 N 92nd St, Suite 203
Scottsdale, AZ 85258
Tel # (480) 661-6197
E-mail: [email protected]
ACADEMIC APPOINTMENTS
- Research Professor; Arizona State University, Department of Chemistry and Biochemistry, January 1, 2000 – January, 2003
- Associate Consultant; Mayo Clinic Scottsdale, Department of Plastic Surgery, March 2000 – June 2000
POST GRADUATE TRAINING
- Mayo Clinic Scottsdale, Department of Plastic & Reconstructive Surgery, Aesthetic and Breast Reconstructive Fellow, Scottsdale, AZ, July, 1999 – Feb, 2000
- Southern Illinois University, Department of Plastic & Reconstructive Surgery, Plastic Surgery Resident, Springfield, IL, July, 1997 – June, 1999
- Southern Illinois University, Department of Plastic & Reconstructive Surgery, Burn Fellow, Springfield, IL, February, 1997 – June, 1997
- University of Washington, Department of Surgery, Senior Research Fellow in Vascular Molecular Biology, Seattle, Washington, July, 1995 – January, 1997
- University of Washington, Department of Surgery, Resident, Seattle, Washington, June 1992 – June 1995
LICENSURE
- State of Arizona 27453
EDUCATION
- University of Arizona College of Medicine, Tucson, Arizona, 1988-1992; M.D., June 1992
- University of California, Berkeley, California, 1984-1988; Major: Religious Studies, Senior Honor Thesis: “Reaction of Early Christianity to Judaism in the Period of the Early Church Fathers,” B.A., May, 1988
HONORS
- Patient Choice Award 2017
- International Association of Plastic Surgeons – Top Plastic Surgeon 2011
- Phoenix Magazine – Top Plastic Surgeon 2010
- Consumer Research Council of America:
- Top Plastic Surgeon 2005, 2006, 2008, 2010, 2011, 2013, 2014
- Top Plastic Surgeon Award for Scottsdale – 101 North Magazine (2005)
- Mayo Clinic Scottsdale:
- 1st place award; Best Poster, Annual Meeting of the American Association of Hand Society
- Southern Illinois University:
- 1st place award; residents forum, Annual Meeting of the American Society of Aesthetic Plastic Surgeons, May, 1999
- 2nd place award; research category, 37th Annual Meeting of the Midwestern Association of Plastic Surgery, May, 1997
- 92% rank; In-service exam, 3/98
- 98% rank; In-service exam, 3/99
- University of Arizona:
- Van Winkle Award for Excellence in Surgical Research, 1992
- Class Representative, Medical Ethics Committee, 1988-1989
- University of California – Berkeley:
- B.A. with Highest Honors
- Dean’s List
- Scholar Athlete of the Year, 1987-1988
- Outstanding Senior Scholar Athlete, 1987-1988
- Ludy Langer Swimming Scholarship, 1987-1988
BOARD CERTIFICATION
- American Board of Plastic Surgery
ACTIVITIES
- United States Masters National Champion: 200 Freestyle Relay, Cupertino, CA, 1996
- University of California Varsity Swim Team, 4-year letter winner, 1984-1988
- Member, U.S. National Team, Caracas, Venezuela, July 1987
AFFLIATIONS
- Plastic Surgery Consultant, Arizona Medical Board
- Member, American Society of Plastic Surgeons
- Member, American Society of Aesthetic Plastic Surgeons
- Lieutenant Commander, United States Naval Reserve, 1996-2007
- Plastic Surgery Technical Advisor; Endor Cor, Inc., Seattle, Washington
- Consultant, Memory Skin Care, Phoenix, Arizona
MEDIA ASSOCIATIONS
- Channel 15 ABC News Plastic Surgery Health Advisor
- KTAR 620 AM Plastic Surgery Consultant
- 101 North Magazine – Expert advisor on Mid-Face Lifts
- Jewish News of Phoenix – Expert author of skin care and laser treatments
GRANT SUPPORT
The Induction of Heat Shock Protein with Hyperbaric Oxygen
- Hyperbaric Oxygen Unit, Memorial Hospital, Springfield, IL Funding – $5,300
The regulation of camp in Skeletal Muscle Exposed to Ischemia-Reperfusion Injury,
- Memorial Medical Center Research Grant Springfield, IL, Funding -$5,500
The use of hypothermia to reduce ischemia-reperfusion injury in the skeletal muscle flap Memorial
- Memorial Medical Center Research Grant, Springfield, IL, Funding -$5,000
The regulation of transcription factors in ischemia-reperfusion injury:
- Edson Foundation, Arizona State and Mayo Clinic Scottsdale, Funding – $50,000
Plastic Surgery Education Foundation, Arizona State University, Funding – $5,000
The role of AOS, a novel antioxidant, in ischemia-reperfusion injury,
- Arizona State University Seed Funding – $20,000
PUBLICATIONS
- Lille S, Sato T, Engrav L, Foy H, Jurkovich J. Necrotizing soft tissue infections; obstacles in diagnosis. Journal of the American College of Surgery 182:7-11, 1996
- Lille S, Rand R, Tapper D, Gruss J; Surgical management of giant cervico-facial lymphatic malformations. Journal of Pediatric Surgery 31:1648-1650, 1996
- Boyle E, Lille S, Allaire E, Clowes A, Verrier E. Chronic Endothelial Cell Injury in Cardiovascular Surgery: Atheroscelrosis. Annals of Thoracic Surgery 63: 885-894, 1997
- Lille S, Daum G, Clowes M, Clowes AW. The Regulation of p42, p44 Mitogen-Activated Protein Kinase in the Injured Rat Carotid Artery. Journal of Surgical Research 70: 178-186, 1997
- Wechselberger G, Scholler T, Lille S. Letter: Retroperitoneal endoscopic neurectomy for nerve entrapment after hernia repair. British Journal of Surgery 84: 1026, 1997
- Boyle E, Lille S, Allaire E, Clowes A, Verrier E. Endothelial Cell Injury in Cardiovascular Surgery: Atherosclerosis. Annals of Thoracic Surgery 64: S47-56, 1997
- Schoeller T, Wechselburger G, Lille S. Letter & Correspondence: A method of reconstructing a natural-looking umbilicus in abdominoplasty. Annals of Plastic Surgery 36:435, 1997
- Lille S, Bayati S, Wechselberger G. Letter & Correspondence: “Durability of prefabricated versus normal random flaps against a bacterial challenge.” Journal of Plastic & Reconstructive Surgery 101:863, 1998
- Wechselburger G, Schoeller T, Lille S, Otto A. Letter: Radial forearm flap donor site complications & morbidity, a prospective study Journal of Plastic & Reconstructive Surgery 101; 874-875, 1998
- Chong KY, Lai CC, Lille S, Chang C, Su CY. Stable overexpression of the constituitive form of heat shock protein 70 confers oxidative protection. Journal of Molecular Cardiology 30; 599-608, 1998
- Lille S, Shoeller T, Roth A, Russell R. Letter & Correspondence: “Adhesion molecules in myocutaneous flaps exposed to ischemic-reperfusion injury” Journal of Plastic & Reconstructive Surgery 101; 1153, 1998
- Wechselburger G, Schoeller T, Stenzl A, Ninkovic M, Lille S, Russell RC. Fibrin glue as a delivery vehicle for autologous urothelial cell transplantation onto a prefabricated pouch. Journal of Urology 160; 583-586, 1998
- Scholler T, Wechselburger G, Otto A, Rainer C, Schwabeggar A, Lille S, Ninkovic M. A scarless technique for the reconstruction of the umbilicus in abdominoplasty. Journal of Plastic & Reconstructive Surgery 102; 1720-1723, 1998
- Lille S, Su CY, Neumeister M, Russel RC, Lai CC. Is heat-shock protein a potential protective mechanism against ischemia-reperfusion injury? Journal of Plastic & Reconstructive Surgery 103; 336-337, 1999
- Lille S, Boyle E, Suchy H, Roth A, Russell R. Augmentation of intracellular cAMP levels prevents endothelial cell activation in response to ischemia-reperfusion injury in skeletal. Journal of Reconstructive MicroSurgery 15; 37-46, 1999
- Lille S, Engrav L, Caps M, Mann R. Eyelid reconstruction following full-thickness burns. Journal of Plastic & Reconstructive Surgery 104; 3:637-645, 1999
- Lille S, Su CY, Suchy H, Lyons S, Russel RC, Lai CC. The induction of HSP72 does not confer physiological protection against ischemia-reperfusion in the rat gracilis muscle. Muscle & Nerve 22; 390-393, 1999
- Paranguo A, Lille S, Brown R. En bloc skin excision for upper extremity cuataneous malignancies in renal allograft patients. Transplantation Proceedings 5;2127-2130,1999
- Su CY, Chong KY, Edelstein K, Lille S, Lai CC. Constituitive HSP70 attenuates hydrogen peroxide-induced membrane lipid peroxidation. Biochemical Biophysical Research Communications 1999; 265:279-284
- Mowlavi A, Lille S, Yashar S, Anderson R. Psychiatric patients who desire aesthetic surgery: identifying the problem patient. Annals of Plastic Surgery 44; 97-106, 2000
- Lille S, Brown RE, Zook E. Free composite nail grafts for chronic nail deformities: an institutional experience. Journal of Plastic & Reconstructive Surgery 105; 2412-2415, 2000
- Wechselberger G, Lille S, Scholler T, Hussel H. Femoral nerve compression following appendectomy. Surgery 127; 115, 2000
- Lille S, Schnur P. Malignant fibrous histicytoma arising in a thoracotomy scar: a case report. Annals of Plastic Surgery 45; 74-77, 2000
- Mowlavi A, Andrews K, Lille S, Verhulst S, Zook EG, Milner S. The management of cubital tunnel syndrome: a meta-analysis of clinical studies. Plast Reconstr Surg 106; 327-334, 2000
- Lille S, Hayakawa W, Neumeister M, Brown RE, Russell RC, Zook EG, Murray K. Continuous post-operative catheter irrigation is not necessary for the treatment of suppurative tenosynovitis: a bi-institutional review. J Hand Surg [Br]. 2000 Jun;25 (3):304-7
- Wechselberger G, Scholler T, Lille S, Suchy H, Russell RC. Bladder reconstruction using tissue engineered prefabricated flaps. J O Urol. 2001 Mar; 165(3):980-5
- Lille S, Lefler SR, Mowlavi A, Suchy H, Boyle EM Jr, Farr AL, Su CY, Frank N, Mulligan DC. Inhibition of the initial wave of NF_kappaB activity in rat muscle reduces ischemia/reperfusion injury. Muscle Nerve. 2001 Apr; 24(4): 534-41.
- Wecheselberger G, Bauer T, Meirer R, Piza-Katzer H, Lille S, Russell RC,
Schoeller T. Muscle prelamination with urothelial cell cultures via fibrin glue in rats. Tissue Eng. 2001 Apr; 7(2):153-9 - Schoeller T, Lille S, Wechselberger G, Otto A, Mowlawi A, Piza-Katzer H.
Histomorphologic and volumetric analysis of implanted autologous Predipocyte cultures suspended in fibrin glue: a potential new source for tissue augmentation. Aesthetic Plast. 2001 Jan-Feb; 25(1):57-63 - Rainer C, Wechselberger G, Bauer T, Neumeister NW, Lille S, Mowlavi A, Piza- Katzer H, Schoeller T. Transplantation of tracheal epithelial cells onto a prefabricated capsule pouch with fibrin glue as a delivery vehicle. J Thorac Cardiovasc Surg. 2001 Jun;121 (6):1187-93
- Schoeller T, Lille S, Bauer T, Wechselberger G, Piza-Katzer H. Gracilis muscle flap with a tissue-engineered lining for experimental bladder wall reconstruction. BJU Intern 2001 Jul;88(1):104-9
- Lille S. Fat transplantation to the face – a useful adjunct to facelift surgery. Journal of Plastic Surgery Products 2002 Nov;(11) 35-37
- Lefler S, Lille S, Humer G, Tucjer R, Murray T, Schoeller T, Mulligan D. Activation time course of activator-protein-1 and the effect of proline DTC during ischemia-reperfusion in rat skeletal muscle. Ann Plast Surg 2002 Dec 49 654-659
- Lille S, Perumean J, McAuthur E. The role releasing the inferior-medial pectoralis
muscle in submuscular breast augmentation. Plast Surg. 2003 Sept;112 (3)919 - Schoeller T, Neumeister MW, Heumer GM, Russel RC, Lille S, Otto-Schoeller A, Wechsclberger G. Biomaterials 2004 Apr,25 (9) 1663-73
- Lille S. Potential concerns of lower eyelid surgical rejuvenation. Plast Reconstr Surg 2005 Aug;116(2) 674-5
- Lille S, Perumean JC.The Lateral and Medial Neclift: an alternative to cervicofacial surgical rejuvenation in the obese patient. Plast Reconstr Surg. 2007 Jan; 119 (1):4323
- Lille S, Blackstone R. Inherited thrombophilias: Are they an important risk factor in bariatric and post-bariatric surgery? Bariatric Times.2008 Jul;2-10
- Lille S. The importance of inherited thrombophilias. Plast Reconstr Surg. 2008 Dec;122 (6):432-3
MANUSCRIPTS SUBMITTED FOR PUBLICATION
- Wechselburger G, Scholler T, Lille S, Otto A, Papp C. Split-Thickness skin graft expansion with tissue expanders: a valuable tool to reduce donor site area. British Journal Plastic & Reconstructive Surgery
- Mowlavi A, Lille S, Zook EG, Brown RE, Milner S, Russell RC. An institutional experience with scalp replants Journal of Reconstructive Microsurgery
- Wechselberger G, Lille S, Scholler T, Stenzyl A, Lyons S, Russell R. Urothelial
cell culture behavior in fibrin glue compared to conventional culture medium.
Journal of Urology - Scholler T, Lille S, Wechselberger G, Suchy H, Lyons S, Russell R. Implanted autologous preadipocytes suspended in fibrin glue: a potential new source for tissue augmentation. Journal of Plastic & Reconstructive Surgery
- Lille S, Pocjkay B, Schnur P. Reducing breast reconstruction into a single stage with the use of immediate nipple reconstruction on pedicle TRAM flaps. Journal of Plastic & Reconstructive Surgery
- Piza-Katzer H, Otto A, Hercezeg E, Wescelberger G, Lille S, Schoeller T. Refinements in reduction mammaplasty using the infra-mammary approach. Annals of Plastic Surgery
- Lille S, Schnur P. Endoscopic forehead lift: is there a difference between absorbable and non-absorbable screws. Journal of Plastic Surgery
- Lille S. The role of the infra-mammary fold in breast augmentation surgery. Journal of Plastic Surgery & Reconstructive Surgery
- Jacoby J, Lille S. The role of operative dissection in breast capsular contracture.. A single surgeon’s review. Journal of Plastic & Reconstructive Surgery.
BOOK CHAPTERS
- Wechselburger G, Schoeller T, Stenzl A, Ninkovic M, Lille S, Russell RC: Chapter 13, Fibrin glue as a delivery vehicle for autologous urothelial cell transplantation onto a prefabricated pouch. In: Stark G.B., Horch R., Tanczos E.(ed): Biological Matrices and Tissue Reconstruction (Heidelberg, Germany: Springer) 1998
- Lille S, Russell R: Chapter 24, Nasal Fractures. In: Shusterman M. (ed): Atlas of Operative Plastic Surgery (Norwalk, CT: Appleton & Lange)
- Lille S, Russell R: Local Tissue Flaps for Facial Reconstruction. PLASTICSURGERY: Indications, Operations, Outcomes (St. Louis, Mo. CV Mosby Company)
- Lille S, Russell R: Finger Tip Injuries. PLASTIC SURGERY: Indications, Operations, Outcomes (St. Louis, Mo. CV Mosby Company)
PUBLISHED ABSTRACTS
- Lille S, Mann R, Engrav L, Caps M. Full-Thickness Skin Grafts for Burned Eyelids Reduces Ectropion Compared to Split-Thickness Skin Grafts. Journal of Burn Care & Rehabilitation 18;1: Suppl S122, 1997
- Lille S, Suchy H, Roth A, Russell R. Augmenting cAMP in muscle flaps reduces ischemia-reperfusion injury. Journal of Reconstructive Microsurgery 14;4:298,1998
- Lille S, Su CY, Suchy H, Lyons S, Russel RC, Lai CC. The induction of HSP72 does not increase tolerance against ischemia-reperfusion in skeletal muscle. Canadian Journal of Plastic Surgery 7;3:157,1999
- Lille S, Mowlavi A, Boyle EM, Su C-Y. Systemically infused Pro-DTC, a potent nuclear factor-KB inhibitor, prevents ischemia-reperfusion injury in the rat skeletal muscle. J Reconstr Micro Surg 16;406:2000
PRESENTATIONS
- Lille S, Bernhard V; “A Retrospective Study of the Pneumatic Tourniquet as an Effective Substitute for Vascular Clamps in Tibial and Popliteal Artery Surgery.” American Federation for Clinical Research, Baltimore, Md., May, 1992
- Lille S, Jurkovich J, “Necrotizing Soft Tissue Infections; Obstacles in Diagnosis.” 64th Annual Meeting of the Pacific Coast Surgical Association, Sacramento, CA., February, 1994
- Lille S, Rand R, Tapper D, Gruss J, “Surgical Management of Giant Cervico-Facial Lymphatic Malformations” 34th Annual Meeting of the Northwest Society of Plastic Surgeons, Whistler, B.C., January, 1996
- Lille S, Rand R, Tapper D, Gruss J, “Surgical Management of Giant Cervico-Facial Lymphatic Malformations” Annual Meeting of the Seattle Surgical Society, Seattle, WA., January, 1996
- Lille S, Daum G, Clowes A. “Role of p42, p44 Mitogen-Activated Protein Kinase in Smooth Muscle Cell Response to Injury In Vivo “ 3rd Annual Meeting of the John Schilling Resident Research Symposium, Seattle, WA, February 6-7,1997
- Lille S, Mann R, Engrav L, Caps M. “Full-Thickness Skin Grafts for Burned Eyelids Reduces Ectropion Compared to Split-Thickness Skin Grafts” Annual Meeting of the American Burn Association, New York, New York, March 17-20, 1997
- Lille S, Suchy H, Roth A, Russell R. “Augmenting cAMP in muscle flaps reduces ischemia-reperfusion injury” Annual Meeting of the Midwest Society of Plastic Surgery St. Louis, Mo., May 29-30, 1997
- Lille S, Mann R, Engrav L, Caps M. “Full-Thickness Skin Grafts for Burned Eyelids Reduces Ectropion Compared to Split-Thickness Skin Grafts” 30th Annual Meeting of the American Burn Association New York, New York. March, 1997
- Weschelburger G, Schoeller T, Lille S, Russell R. Transplantation of Autologous cultured urothelial cells onto pre-fabricated capsule in rats. 8th Congress European Section IPRAS, June, 1998
- Lille S, Suchy H, Roth A, Russell R. “Elevation of endothelial cAMP levels
reduces ischemia-reperfusion injury in the rat gracilis muscle” Annual Meeting of the American Society of Reconstructive Microsurgery Scottsdale, AZ, January 11, 1998 - Lille S, Suchy H, Roth A, Russell R. “Augmentation of intracellular cAMP levels prevents endothelial cell activation in response to ischemia-reperfusion injury in the rat gracilis muscle” Annual Meeting of the Plastic Surgery Research Council, Loma Linda, Ca., April 4-9, 1998
- Lille S, Suchy H, Roth A, Russell R. “Augmentation of intracellular cAMP levels prevents endothelial cell activation in response to ischemia-reperfusion injury in the rat gracilis muscle” Annual Meeting of the American Association of Plastic Surgeons, Montreal, Canada, May 15-18, 1998
- Lille S, Schoeller T, Wescelberger G, Neumeister M, Russell RC. “Histomorphologic and volumetric analysis of implanted autologous preadipocytes suspended in fibrin glue: A potential new source for tissue augmentation” American Society of Aesthetic Plastic Surgery Annual Meeting, Dallas, TX, May 14-19, 1999
- Lille S, Mowlavi A, Boyle E, Suchy H, Farr A, Neumeister M, Russell RC. “Inhibition of NF-kB in the skeletal muscle flap does not reduce ischemia-reperfusion injury” Annual Meeting of the Plastic Surgery Research Council Pittsburgh, PA, May 21-25, 1999
- Lille S, Su CY, Suchy H, Neumeister M. “Heat-Shock Protein 72 does not reduce Ischemia-Reperfusion Injury in a Rat Skeletal Model” Annual Meeting of the Association of Canadian Plastic Surgery, Montreal, Canada, June 25-28, 1999
- Lille S, Mowlavi A, Boyle EM, Suchy H, Neumeister MA. “Nuclear Factor-kappa B inhibition reduces ischemia-reperfusion injury in skeletal muscle” Annual Meeting of the American Society of Microsurgery, Miami, FLA, January 5-8, 2000
- Lille S. “Role of transcription factors in ischemia reperfusion injury: a potential strategy for pharmacological manipulation” Seminar, Department of Biochemistry, Arizona State University, Tempe, AZ, October 15, 1999
- Lille S, Perumean J, Lefler S. AP-1 activation and inhibition in an ischemia reperfusion skeletal muscle model. Annual Meeting of the Plastic Surgery Research Council, Boston, MA, April, 2002
- Lille S, The evolution of the Mid-Cheek Lift. Why it enhances facelift surgery. Rabin Medical Center, Tel Aviv, Israel, May 2002
POSTERS
- Rubis B, Lille S, Haws M, Russell R. Division of a Pedicled TRAM Flap for Cardiac Revascularization. Annual Meeting of the American Society of Reconstructive Microsurgery, January 1998
- Lille S, Daum G, Clowes M, Clowes A. “Role of Mitogen-Activated Protein Kinase and Heparin in Smooth Muscle Cell Response to Injury In-Vivo “30th Annual Meeting of the Association for Academic Surgery, Chicago, IL, November 13-16, 1996
- Weschelburger G, Schoeller T, Lille S, Russell R. Transplantation of Autologous
cultured urothelial cells onto pre-fabricated Capsule in rats. 44th Annual Meeting of the Plastic Surgery Research Council, Loma Linda, CA, April, 1998 - Lille S, Hayakawa W, Neumeister M, Brown RE, Russell RC, Zook EG, Murray K. Continuous post-operative catheter irrigation is not necessary for the treatment of suppurative tenosynovitis: a bi-instituitional review Annual Meeting of the American Society of Hand Surgery, Miami, FLA, January 5-8, 2000
- Mowlavi A, Lille S, Neumeister MA, Suchy H, Russell R. Regional hypothermia reduces ischemia-reperfusion injury in the rat skeletal muscle model. Annual Meeting of the American Society of Reconstructive Microsurgery, Miami, Fla. Jan 5-8, 2000
- Lille S, Perumean J, Lefler S. Inhibition of AP-1 and the role of apoptosis in a rat skeletal muscle model of ischemia-reperfusion. Annual Meeting of the American Society of Reconstructive Microsurgery, Hawaii, Jan 14-17, 2003